James Lab
The goal of the James lab is to learn how human B cells differentiate into long-lived antibody-secreting plasma cells. We would like to better understand how dysregulated B cell differentiation can contribute to plasma cell-associated immune diseases, including primary immune deficiency, rheumatoid arthritis and lupus. We leverage what we learn to develop B cell-based therapies.
Explore the Lab
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- October 22, 2024 Unlocking the Immune System’s Role in a Post-Transplant Malady
- July 2, 2024 Engineered Plasma Cells Shown to Stop Leukemia in Small-Animal Model
- April 30, 2024 Seattle Children’s Researchers Highlight Achievements in Novel Therapies at Gene and Cell Therapy Meeting
- August 1, 2023 James Lab moves from Jack MacDonald Building to Building Cure!
- June 15, 2023 Plasma Cell Secretion Proof-of-Concept Findings Published
- May 16, 2023 Seattle Children’s Researchers Share Progress at American Society of Gene and Cell Therapy Annual Meeting
- October 16, 2022 Engineering B Cells for Future Therapies
- September 26, 2022 Aaron Ramonett joins the lab!
- August 9, 2022 Greg Asher joins the lab!
- July 5, 2022 Anna Helmers joins the lab!
- May 23, 2022 Sam Dawson joins the lab!
- March 1, 2022 Ameena and Parnal Join the Lab!
- November 21, 2021 Collaboration with Be Biopharma
- December 2, 2019 Rupa and Naomi Join the Lab!
- July 15, 2019 Andee Ott Joins the Lab!
- March 15, 2019 Tyler Hill Joins the Lab!