Search Search

About the Center

Our investigators tackle some of the toughest childhood diseases and address our nation’s biggest health challenges.

The overarching goal of the Center for Immunity and Immunotherapies (CIIT) at Seattle Children's Research Institute is to advance our understanding of human diseases impacting the human immune system and to harness the therapeutic potential of immunology to treat disease. Our dynamic group of distinguished experts across multiple disciplines work together to solve some of the immune system's most complex problems. Many of our researchers are physician-scientists who treat patients in the Immunology, Rheumatology, Nephrology and Gastroenterology clinics at Seattle Children’s Hospital. In order to achieve our ultimate goal of applying what we learn to the care of our patients, our research extends full-circle from clinical questions to laboratory-based investigation and back to patients.

Harnessing the Immune System’s Healing Potential

We start with the premise that a child's immune system has vast healing potential. Thus, we are focused on harnessing that potential and manipulating the immune system to treat diverse pediatric diseases, including immune deficiency, systemic autoimmunity, infection, allergy, cancer, and the rejection of organ transplants. In these endeavors, our scientists are working to design improved diagnostic tools for primary immune deficiency syndromes, to devise innovative vaccine strategies, and to develop novel gene and cell engineering technologies for the treatment of human protein deficiencies, immunodeficiency syndromes and systemic autoimmune diseases.

Who We Are

The Center for Immunity and Immunotherapies (CIIT) is one of eight research centers forming Seattle Children's Research Institute. We are located within Seattle Children's Research Institute's B. Wayne Hughes Building, also known as Building Cure, at 1920 Terry Ave. in downtown Seattle.

Dr. David Rawlings, director of CIIT, leads a distinguished group of experts that includes 14 principal investigators and over 80 research scientists, graduate students, and post-doctoral fellows, who work together to solve some of the immune system's most complex problems..

Leadership

  • David J Rawlings, MD

    David J Rawlings, MD

    Director, Center for Immunity and Immunotherapies, Seattle Children’s Research Institute; Director, Program for Cell and Gene Therapy, Seattle Children’s Research Institute; Chief, Division of Immunology, Seattle Children's Hospital

  • Bruce Torbett, PhD

    Bruce Torbett, PhD

    Associate Director, Center for Immunity and Immunotherapies, Seattle Children's Research Institute

 

Center for Immunity and Immunotherapies

For questions or inquiries,
email: ciitadmin@seattlechildrens.org.

Physical Address

1920 Terry Ave.
Seattle, WA 98101

Mailing Address

M/S CURE 6/7
PO Box 5371
Seattle, WA 98145-5005

Seattle Children’s complies with applicable federal and other civil rights laws and does not discriminate, exclude people or treat them differently based on race, color, religion (creed), sex, gender identity or expression, sexual orientation, national origin (ancestry), age, disability, or any other status protected by applicable federal, state or local law. Financial assistance for medically necessary services is based on family income and hospital resources and is provided to children under age 21 whose primary residence is in Washington, Alaska, Montana or Idaho.