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Craniofacial Image Repository for Analysis of Shape

CIRAS

Principal Investigators: Drs. Carrie Heike and Michael Cunningham  

While treatment of craniofacial malformations has dramatically improved in the past two decades, methods for assessment and documentation of craniofacial variation and malformations often rely on non-standardized, subjective descriptions. The CIRAS study is modernizing this by developing a repository of 3-D images on individuals with and without conditions that affect craniofacial features and tools to measure the severity of craniofacial malformations before and after treatment. We plan to enroll 5,000 individuals in this study. Our ultimate goal is to improve how we classify and assess craniofacial conditions and treatment outcomes.

Aim 1

To create a repository for 3-D images and DNA for future research into the etiology, natural history and treatment outcomes of typical and atypical craniofacial features.

Aim 2

To develop methods to classify and quantify the severity of craniofacial malformations in craniofacial conditions affecting the head and face using 3-D surface images.

Aim 3

To develop methods to classify and quantify severity of craniofacial skeletal malformations and soft tissues (including the airway) using CT data.

Contact

For more information, contact Laura Stueckle.

Seattle Children’s complies with applicable federal and other civil rights laws and does not discriminate, exclude people or treat them differently based on race, color, religion (creed), sex, gender identity or expression, sexual orientation, national origin (ancestry), age, disability, or any other status protected by applicable federal, state or local law. Financial assistance for medically necessary services is based on family income and hospital resources and is provided to children under age 21 whose primary residence is in Washington, Alaska, Montana or Idaho.