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The Promise of Immunotherapy

Immunotherapy Trials

Immunotherapy holds much promise with its ability to target tumor cells specifically. Building on that promise, doctors and researchers at Seattle Children’s have begun a series of Phase 1 trials called BrainChild. These trials test chimeric antigen receptor (CAR) T-cell therapy in children and young adults with recurrent or refractory CNS tumors, including DIPG and DMG.

Read more about how CAR T-cell therapy works.

BrainChild Studies: Phase 1 Trials

Seattle Children’s offers Phase 1 clinical trials using CAR T-cell therapy for brain and CNS tumors in children and young adults. These include BrainChild-01, -02, -03 and -04.

Seattle Children’s runs simultaneous clinical trials. This means that rather than waiting for the results of one trial before starting the next one, we share and apply knowledge that we gain from the trials while they are still ongoing. This process allows us to learn from open trials while also researching new treatments.

For more information about BrainChild studies, call 206-987-2106 or send us an email.

Seattle Children’s complies with applicable federal and other civil rights laws and does not discriminate, exclude people or treat them differently based on race, color, religion (creed), sex, gender identity or expression, sexual orientation, national origin (ancestry), age, disability, or any other status protected by applicable federal, state or local law. Financial assistance for medically necessary services is based on family income and hospital resources and is provided to children under age 21 whose primary residence is in Washington, Alaska, Montana or Idaho.