Elizabeth Lawlor, MD, PhD

Elizabeth Lawlor, MD, PhD
"Every child with cancer deserves the chance to grow up to realize their dreams and every family deserves access to the best possible, state-of-the-art care. Through research now, and by educating the doctors and researchers of tomorrow, my passion is to help bring hope and cures to kids with cancer everywhere."

  • Biography

    I am a physician scientist, researcher, educator, and advocate for children. My research is focused on understanding the fundamental biology of Ewing sarcoma, an aggressive bone and soft tissue tumor that impacts all ages with peak incidence in adolescents and young adults.

    I completed my MD at McMaster University and clinical training in pediatric hematology-oncology and PhD in pathology at the University of British Columbia in Vancouver, Canada. Following post-doctoral training at University of California, San Francisco, I began my career as an independent investigator at Children's Hospital Los Angeles and the University of Southern California. From 2010 to 2020, I was a faculty member at the University of Michigan, where my lab continued to focus its research on basic and translational studies of pediatric solid tumors. While at Michigan, I also served as director of the Cancer Biology PhD graduate and T32 training programs and as associate director of education and training at the Rogel Cancer Center.

    In June 2020, I joined Seattle Children's Research Institute where I am associate director of the Ben Towne Center for Childhood Cancer and Blood Disorders Research. I am also a professor of pediatrics at the University of Washington, adjunct professor in the Department of Laboratory Medicine and Pathology, and an affiliate investigator in the Clinical Research and Human Biology Divisions of the Fred Hutchinson Cancer Center.

    My lab has been continuously funded by grants from the NIH/NCI, AACR-Stand Up to Cancer, Alex's Lemonade Stand Foundation, St. Baldrick's Foundation, the V Foundation, as well as numerous smaller funding agencies.

    Research Description

    We use state-of-the-art model systems and technologies to elucidate drivers of sarcoma progression. We are specifically interested in identifying differences between cancer and normal development. The overarching hypothesis is that this research will identify tumor-specific vulnerabilities that can be targeted by innovative therapies that will spare normal tissues and be less toxic to growing children.

    Key areas of focus: sarcoma biology, epigenetics, cell plasticity and tumor heterogeneity, metastasis, tumor: microenvironment crosstalk

    ABOUT MY WORK

    https://www.seattlechildrens.org/research/centers-programs/childhood-cancer/our-labs/lawlor-lab/

    Research Focus Area

    Novel Therapeutics

  • Related Resources

    • Lawlor Lab

      Lawlor Lab

      The goal of the Lawlor Lab is to discover how hijacking of normal developmental biologic programs contributes to the origin and progression of childhood cancer.

  • Awards and Honors

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  • Publications

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  • Clinical Trials and Research Studies

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